Welcome to the Intellectual Disability Cell Bank
Lymphoblast, fibroblast intellectual disability cell bank
The intellectual disability cell bank is a facility in Genetics Research Center (GRC), University of Social Welfare and Rehabilitation Sciences (USWR) in Iran, collaborating with Max Planck Institute for Molecular Genetics( MPIMG) in Germany. This facility provides an essential service to the scientific community by establishing, analyzing and banking cell cultures derived from patients affected by intellectual disability. This cell bank, sponsored by Iran's National Elites Foundation (INEF), Deputy of Research in USWR and GENCODYS [funded by European Union under the 7th framework program (Health- 241995)] grants, consists of specimens (dermal fibroblasts, lymphoblasts) derived from patients with intellectual disability in which their causing genes and mutations have been identified. The bank provides cell lines for future functional study of causing genes in transcription and translation levels specially genes which are expressed in the brain or other ones with proteins involved in brain function.
The clinical data concerning the patients are collected in a continuously updated cell bank database. The cell bank is supported by experts for clinical information revision.
According to ethical and legal recommendations, the samples have been taken for analysis and cell banking after written donor informed consent, approved by the regional ethics committee of the University of Social Welfare and Rehabilitation Sciences for medical research.